What do you know about the six uses of magnesium sulfate?

Magnesium sulfate 6 applications
Oral
1, cathartic effect: oral administration because it is not absorbed, the formation of certain osmotic pressure in the intestine, so that the intestine to maintain a large amount of water, intestinal volume expansion, intestinal expansion, stimulate intestinal peristalsis, so that the intestinal contents quickly enter the large intestine, Discharge the water sample of stool.

2. Choledochism: oral administration of high concentration (33%) magnesium sulfate solution or direct infusion of ducts into the duodenum could stimulate duodenal mucosa, reflexively induce relaxation of sphincter of the common bile duct, constriction of gallbladder, and promote gallbladder emptying. Produce the effect of gallbladder. Clinical use for obstructive jaundice and chronic cholecystitis.

3the effect on the central nervous system: to increase the concentration of magnesium ions in extracellular fluid, to inhibit the central nervous system, to treat preeclampsia and eclampsia in clinic, to treat preeclampsia and eclampsia, and to treat preterm labor.

4. the effect on cardiovascular system: injection of too much magnesium ion can directly relax the peripheral vascular smooth muscle, make vascular dilatation and decrease blood pressure. It can be used in patients with frequent attacks and poor treatment of angina pectoris, and it is better for patients with hypertension. Often used in pregnancy hypertension.

5. Treatment of hypomagnesemia: normal serum magnesium concentration is between 0.8~1.05mmol / L and serum magnesium is lower than 0. 7 5mmol/L was hypomagnesemia.

6, anti-inflammatory detumescence: 50% magnesium sulfate solution topical hot compress, has the effect of anti-inflammation and detumescence.

Six points for attention of magnesium Sulfate
1. If a large amount of solution is taken during catharsis, it may lead to dehydration by absorbing a large amount of water from the tissue. The gastrointestinal tract has ulcers, where damage, easy to cause a large amount of magnesium ion absorption and lead to poisoning. Intestinal bleeding patients, acute abdomen patients and pregnant women, menstrual women prohibited this product diarrhea.

2, intravenous magnesium sulfate often causes flushing, sweating, dry mouth and other symptoms, rapid intravenous injection can cause nausea, vomiting, panic, dizziness, individual occurrence of nystagmus, slow injection speed symptoms can disappear.

3, myocardial damage, respiratory disease, severe renal insufficiency, cardiac block should be used carefully or not.

4, Renal insufficiency, injection should be reduced, anuria should be banned, because of the accumulation of magnesium poisoning.

5, there is a certain danger in intravenous drip, it must be carried out slowly, and 10% calcium gluconate injection is prepared for rescue. When poisoning should be immediately slow intravenous injection of calcium chloride or calcium gluconate emergency rescue. Dialysis therapy can quickly remove magnesium ions in the body.

6. The knee tendon reflex examination was done regularly before and during each medication, and the respiratory times were measured. Observe whether there are symptoms of magnesium poisoning in time.

Third, incompatibility taboo
Contraindications for compatibility with magnesium sulfate are polymyxin B sulfate, streptomycin sulfate, calcium gluconate, dobutamine hydrochloride, procaine hydrochloride, tetracycline, penicillin and naphthoxicillin, vitamin K1.

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